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As with other sedatives and hypnotics, elderly or debilitated patients may well respond to barbiturates with marked pleasure, depression, or confusion. The systemic effects of exogenous hydrocortisone and endogenous hydrocortisone (cortisol) may be diminished by phenobarbital. Therefore, this merchandise needs to be administered with warning to cli
Most reports of clinically major drug interactions happening with the barbiturates have involved phenobarbital. Having said that, the appliance of those facts to other barbiturates seems valid and warrants serial blood level determinations on the applicable drugs when you can find a number of therapies.Period of action, and that is connected to the